Tesamorelin Facts and Dosing
Tesamorelin is a 44-amino-acid long peptide that was created as a synthetic analog of growth hormone-releasing hormone (GHRH), which is normally produced in the hypothalamus.
It stimulates the pituitary gland in your brain to increase your body’s natural production of growth hormone (GH).

Tesamorelin has many health benefits:
- Reduction in Visceral Fat: Tesamorelin has consistently shown its ability to reduce visceral fat, particularly the fat accumulated in the abdominal region. Multiple studies have reported statistically significant reductions in abdominal fat after treatment with tesamorelin.
- Improvement in Lipid Profile: Positive case studies have noted improvements in lipid profiles with tesamorelin treatment. This includes reductions in triglycerides and LDL cholesterol levels, which are important for cardiovascular health.
- Enhanced Insulin Sensitivity: Some studies have reported improvements in insulin sensitivity in individuals treated with tesamorelin. This is crucial for individuals with lipodystrophy who often experience metabolic disturbances.
- Positive Impact on Quality of Life: Tesamorelin treatment has been associated with improved quality of life in some patients with HIV-associated lipodystrophy. This improvement may be attributed to the reduction in abdominal fat and the accompanying metabolic and cosmetic benefits.
- Tolerability: In general, tesamorelin has been well-tolerated in clinical trials and case studies. Common side effects include mild injection-site reactions and joint pain. Severe adverse events are relatively rare.
Dosing:
- 1mg in the late evening, at least 1 hour after eating last meal.
- 1mg in the morning, on an empty stomach. Do not eat or drink any calories for roughly an hour after the morning dose.
- Take for 5 days, then take two days off.
- Do not use for more than 6 months at a time.
- Weeks on = Weeks off.
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