MOTS-C Facts & Dosing

"MOTS-c" refers to a mitochondrial-derived peptide with potential roles in regulating metabolism and promoting health. MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-C) is a relatively new area of research, and positive case studies may be limited or not widely available.

Here are some general points related to MOTS-c and its potential benefits based on research up to that point:
  • Improved Metabolic Health: MOTS-c has shown promise in preclinical studies as a regulator of metabolism. It may enhance insulin sensitivity, which can be beneficial for individuals with insulin resistance and type 2 diabetes.
  • Energy Regulation: MOTS-c appears to influence energy production within cells by optimizing mitochondrial function. This could potentially lead to increased energy levels and improved endurance.
  • Muscle Health: Some research has suggested that MOTS-c may have a positive impact on muscle health, including muscle mass and strength.
  • Anti-Aging Properties: MOTS-c has been explored for its potential anti-aging effects, including its role in regulating mitochondrial function, which is closely linked to the aging process.
  • Cardiovascular Health: There is some evidence to suggest that MOTS-c might have a protective effect on the cardiovascular system by reducing inflammation and improving vascular function.
  • Weight Regulation: Research in animals has indicated that MOTS-c may play a role in weight regulation and fat metabolism.
  • Potential Therapeutic Applications: MOTS-c is an area of active research, and its therapeutic potential is being explored in various contexts, including metabolic disorders and age-related conditions.

Dosing Recommendations: 

  • Taken every 3 days. 
  • Can be dosed at 5mg or 10mg. 
  • Preferred dosage for optimal results is 10mg every 3 days. 
  • Do not use for longer than 8 weeks. 
  • Take 6 months rest before dosing again. 

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