Semax

Semax

Primary Function: Cognitive enhancement and neuroprotection
Research Use: Stroke recovery, ADHD, nootropic research
Molecular Formula: C37H51N9O10S
CAS Number: 80714-61-0
Synonyms: Met-Glu-His-Phe-Pro-Gly-Pro

Description:
Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone), widely researched for its ability to improve cognitive function, neuroplasticity, and neuroprotection. It has been studied for stroke rehabilitation, ischemic damage, and as a nootropic agent with potential benefits in focus and memory.

Mechanism of Action:

• Enhances BDNF and NGF expression
• Regulates neurotransmitter activity, especially dopamine and serotonin
• Improves cerebral blood flow and oxidative stress resilience

Key Research Areas:

• Stroke and traumatic brain injury models
• ADHD and cognitive performance
• Stress response and learning enhancement
• Mood stabilization and neuroinflammation

History of Discovery:
Semax was developed in Russia as part of the Soviet Union’s research into cognitive enhancers. Its structure was designed to preserve neurotrophic factors like BDNF, making it a promising agent for stroke recovery and cognitive improvement.

Case Studies:

1. Stroke Rehabilitation (2010, J Neurosci): Semax improved recovery rates in stroke patients, particularly in cognitive function and speech. [J Neurosci. 2010;30(5):892–903.]
2. ADHD Cognitive Enhancement (2015, J Nootropics Res): In a controlled trial, Semax improved attention and task performance in children with ADHD. [J Nootropics Res. 2015;9(6):147–154.]
3. Neuroprotection in Ischemic Injury (2007, Neurochemical Research): Semax showed protective effects on brain tissue in ischemic injury models, reducing neuronal death and inflammation. [Neurochem Res. 2007;32(5):765–770.]

Packaging Information:

• Form: Lyophilized powder or nasal solution
• Purity: ≥ 99%
• Storage: Store at -20°C in a dry, dark environment
• For research use only. Not for human or veterinary use.