PE 22-28
PE 22-28
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PE-22-28 is a synthetic peptide derived from the neuropeptide spadin, which modulates TREK-1 potassium channels involved in mood regulation.
History & Development
PE-22-28 was developed as a potential alternative to traditional antidepressants, targeting TREK-1 channels to improve synaptic activity and neuronal function.
Potential Benefits & Mechanism of Action
- Mood Enhancement: May have antidepressant-like effects.
- Neuroprotection: Supports neuronal survival and plasticity.
- Stress Resilience: Helps regulate emotional responses.
Research & Clinical Studies
Animal studies suggest that PE-22-28 exhibits antidepressant effects similar to SSRIs but with a more rapid onset of action. Human trials are needed to confirm efficacy.
