Methylene Blue Capsules
Methylene Blue Capsules
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Methylene Blue (MB) is a synthetic compound with a long history of use in medicine, now being actively explored in research settings for its neuroprotective, mitochondrial-enhancing, and cognitive-boosting properties. In its pharmaceutical-grade form, Methylene Blue has demonstrated potential in supporting cellular respiration, reducing oxidative stress, and enhancing brain energy metabolism—making it a highly versatile molecule in longevity and neuroscience research.
Mechanism of Action
Methylene Blue acts as an alternative electron carrier within the mitochondrial electron transport chain, particularly between complexes I and III. This bypasses dysfunctional segments of the chain and enhances ATP production efficiency.
It also functions as a potent antioxidant, reducing reactive oxygen species (ROS) while maintaining redox balance. At lower doses, MB may enhance memory, mitochondrial activity, and cognitive performance, while at higher doses it may act as a pro-oxidant—making precise dosing critical in research models.
Key Research Findings
✅ Enhances Mitochondrial Function
Improves cellular respiration and energy production by optimizing oxidative phosphorylation, particularly under stress or hypoxic conditions.
✅ Neuroprotective & Cognitive Effects
Shown to improve memory retention, reduce neuronal death, and enhance cerebral blood flow in preclinical studies. MB is being researched for use in Alzheimer’s and Parkinson’s disease models.
✅ Reduces Oxidative Stress
Scavenges free radicals and helps preserve mitochondrial integrity by modulating redox cycling.
✅ Anti-Microbial & Anti-Viral Properties
Historically used as an antimicrobial agent. Current research includes interest in its antiviral effects when combined with light or other therapies.
Research Applications
Methylene Blue capsules are used in research models studying:
- Mitochondrial dysfunction and energy metabolism
- Neurodegenerative diseases (Alzheimer’s, Parkinson’s)
- Cognitive enhancement and memory retention
- Oxidative stress and redox biology
- Longevity and bioenergetics
Clinical Research Highlights
📌 Rojas et al., CNS Neuroscience & Therapeutics (2012)
“Low-dose methylene blue improves mitochondrial respiration and reduces neurodegeneration in Alzheimer’s disease models.”
📌 Shiba et al., Neurotoxicity Research (2020)
“Methylene blue demonstrated memory-enhancing effects and improved synaptic plasticity markers in aged animal models.”
📌 Wen et al., Frontiers in Aging Neuroscience (2021)
“MB mitigated cognitive deficits and oxidative stress induced by sleep deprivation, suggesting relevance in cognitive fatigue and brain aging.”
Molecular Profile
Property | Details |
---|---|
Compound | Methylene Blue (U.S.P. grade) |
CAS Number | 61-73-4 |
Molecular Formula | C₁₆H₁₈ClN₃S |
Molecular Weight | 319.85 g/mol |
Capsule Format | 5mg / 10mg / 20mg (customizable) |
Purity | ≥99% (HPLC Verified) |
Appearance | Deep blue crystalline powder |
Storage | Store in cool, dry conditions; avoid sunlight |
⚠️ Disclaimer
Methylene Blue Capsules are offered strictly for research use only. Not for human or veterinary consumption. Not a drug, dietary supplement, or cosmetic. Purchasers must be qualified professionals conducting authorized research.
