L-Glutamine
L-Glutamine
Base Peptides are intended for licensed medical professionals and experienced researchers. Reconstitution required. Dosing and use instructions are not provided.
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L-Glutamine — Research-Grade Amino Acid
L-Glutamine is a conditionally essential amino acid (formula C5H10N2O3) widely studied for roles in nitrogen transport, acid-base balance, and as a key substrate for rapidly dividing cells. This page summarizes specifications and common research focuses in cell, tissue, and performance physiology models.
- Chemical name: L-Glutamine
- Molar mass: 146.14 g/mol
- Appearance: White crystalline powder
- Purity: 99%+ (lot-tested; HPLC/MS)
- Solubility: Water soluble (warm water improves dissolution)
- • Major nitrogen donor supporting nucleotide and amino-sugar synthesis
- • Fuel for enterocytes and certain immune cell populations
- • Participates in acid–base balance via renal ammoniagenesis
- Barrier function in epithelial/intestinal models
- Cell growth, recovery, and stress-response signaling
- Glycogen repletion and exercise physiology paradigms
- Immune cell metabolism & cytokine dynamics
Descriptions are for laboratory research design only.
Background & Rationale
L-Glutamine is among the most abundant free amino acids in plasma and skeletal muscle. Under catabolic stress, demand may exceed endogenous synthesis capacity, which is why it is often described as “conditionally essential” in specific models. In vitro and in vivo research frequently focuses on its roles in nitrogen shuttling, maintaining redox and osmotic balance, and supporting rapidly proliferating tissues.
Specifications & Handling
- Grade: Research-grade; manufactured in ISO-audited facility
- Additives: None unless specified per lot
- Storage (dry): Tightly sealed at 15–25 °C; avoid humidity
- In-solution stability: Prepare fresh where possible; refrigerate and minimize repeated freeze–thaw if aliquoted
- Reconstitution guidance: Dissolves in water; gentle heating and stirring aid dissolution
- pH considerations: Near neutral; adjust per protocol as needed
- Compatibility: Validate with other actives, buffers, and media in your protocol
Common Research Paradigms
Cell Culture & Tissue
- Supplementation in media for proliferative cell lines
- Assessment of barrier integrity in epithelial models
Metabolism & Performance
- Glycogen repletion timing & nitrogen balance models
- Markers of fatigue, recovery, and stress signaling
Immunometabolism
- Glutaminolysis and cytokine dynamics in immune cells
- Redox homeostasis and antioxidant pathways
Regulatory & Use Notice
Sold strictly for laboratory research. Not a drug, food, or cosmetic. No instructions for human use are provided. Buyer is responsible for safe handling and compliance with local regulations.
