HCG 5,000IU

HCG (Human Chorionic Gonadotropin) – Endocrine Research for Hormonal Regulation & Fertility

Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone best known for its role in reproductive biology. In research contexts, HCG is studied for its ability to stimulate luteinizing hormone (LH) activity, influence testosterone production, and preserve fertility and gonadal function in both male and female models. It is also used in endocrine research related to hypothalamic-pituitary-gonadal (HPG) axis function and hormonal restoration following suppression.

Mechanism of Action

HCG mimics the biological activity of luteinizing hormone (LH) by binding to the LH/CG receptor on Leydig cells in the testes or theca cells in the ovaries. This stimulates the production of testosterone in males and ovulation in females. In male research models, HCG is frequently used to maintain intratesticular testosterone levels during exogenous hormone administration (e.g., during anabolic steroid or testosterone replacement protocols).

Key Research Benefits

✅ Stimulates Endogenous Testosterone Production

By acting on LH receptors, HCG promotes natural testosterone synthesis and prevents testicular atrophy in suppressed models.

✅ Preserves Fertility During Suppression

Often studied for its role in maintaining spermatogenesis during hormone therapy.

✅ Supports Hormonal Recovery

HCG is commonly included in post-cycle therapy (PCT) protocols to stimulate the hypothalamic-pituitary-gonadal axis.

✅ Induces Ovulation in Female Models

Used to study ovarian response and follicle rupture during reproductive research.

Research Applications

• Hypogonadism models
• Male fertility and spermatogenesis studies
• Hormonal suppression and recovery protocols
• Female ovulation and fertility studies
• Endocrine signaling and pituitary feedback loops

Clinical & Preclinical Highlights

📌 Bhasin et al., Journal of Clinical Endocrinology & Metabolism (2001)

“HCG maintained intratesticular testosterone concentrations in men receiving testosterone enanthate, suggesting a role in preserving spermatogenesis during androgen therapy.”

📌 WHO Research Program on Male Fertility (1990s)

“HCG administration during testosterone-induced suppression preserved fertility in long-term male contraceptive trials.”

📌 Practice Committee of the ASRM (2020)

“HCG remains a gold-standard agent in assisted reproduction for triggering ovulation and luteal support.”

Molecular Profile

⚠️ Research Use Only

This product is intended for in-vitro laboratory research only. It is not approved for human or veterinary use, nor for diagnostic or therapeutic applications. All purchasers must be qualified professionals operating within approved research frameworks.