Tesofensine Tablets 500mcg

Tesofensine is a novel triple monoamine reuptake inhibitor (TMRI) that is being developed for the treatment of obesity. It works by increasing levels of dopamine, serotonin, and norepinephrine in the brain. These neurotransmitters play a role in appetite regulation, energy expenditure, and mood.

Tesofensine has been shown to be effective in promoting weight loss and improving metabolic health in clinical trials. In a 24-week study, participants who received tesofensine lost an average of 5-10% of their body weight, compared to those who received a placebo. Tesofensine also led to improvements in insulin sensitivity, cholesterol levels, and blood pressure.

In addition to its weight loss benefits, tesofensine has also been shown to have cognitive benefits and antidepressant effects. It has been shown to improve learning and memory, and to reduce symptoms of depression.

Potential Benefits & Mechanism of Action

• Appetite Suppression: Reduces food cravings and caloric intake.

• Metabolic Enhancement: Boosts energy expenditure and fat oxidation.

• May enhance mood and focus through neurotransmitter modulation.

Tesofensine works by increasing neurotransmitter levels in the brain, leading to reduced hunger and enhanced metabolic rate.

Phase II clinical trials demonstrated that Tesofensine led to significant weight loss—greater than current pharmaceutical options—with sustained effects over six monthals.