RAD

RAD-140 (Testolone)

Primary Function: Lean muscle growth, androgenic pathway activation, fat loss support
Research Use: Sarcopenia, anabolic resistance, hormone replacement alternatives
Molecular Formula: C20H16ClN5O2
CAS Number: 1182367-47-0
Synonyms: Testolone, RAD140, RAD-140 SARM

Description:
RAD-140, also known as Testolone, is a potent Selective Androgen Receptor Modulator (SARM) designed to promote anabolic activity in muscle and bone without the unwanted side effects associated with traditional anabolic steroids. RAD-140 binds with high affinity to androgen receptors in muscle and skeletal tissues, making it a prime candidate for research into muscle wasting disorders, hormonal decline, and age-related sarcopenia.

Mechanism of Action:

• Selectively binds to androgen receptors in muscle and bone tissue
• Stimulates protein synthesis and lean mass development
• Avoids aromatization or conversion to estrogen
• Minimal interaction with prostate and other androgen-sensitive tissues

Key Research Areas:

• Muscle preservation and hypertrophy studies
• Hormone replacement therapy research
• Fat loss and metabolic efficiency
• Osteoporosis and bone density improvement

History of Discovery:
RAD-140 was developed by Radius Health Inc. as part of their investigation into safer alternatives to testosterone therapy. Its high tissue selectivity and strong anabolic-to-androgenic ratio quickly made it a leading research compound in the SARM category.

Case Studies:

1. Muscle Growth Without Prostate Impact (2010, J Gerontol A Biol Sci Med Sci): RAD-140 induced significant lean tissue gains in primates without stimulating prostate tissue. [J Gerontol A Biol Sci Med Sci. 2010;65(10):1083–1093.]
2. Neuroprotective Potential (2013, Endocrinology): Demonstrated protective effects on hippocampal neurons in androgen-deficient models. [Endocrinology. 2013;154(9):3188–3197.]
3. Anabolic Effects in Aging Muscle (2016, Muscle Nerve): Improved strength, endurance, and anabolic markers in aging rodents. [Muscle Nerve. 2016;54(6):1021–1031.]

Packaging Information:

• Form: Research-grade tablets 
• Purity: ≥ 99%
• Storage: Store at room temperature in a dry, dark place
• For research use only. Not for human or veterinary use.