Base Peptide Guide - November 2025 Edition

Base Peptide Guide - November 2025 Edition

Base Peptide Guide

November Edition – For Researchers & Enthusiasts

Peptide Spotlight

  • Obesity – Semaglutide (GLP-1 Analogue):
    Semaglutide is a cutting-edge peptide targeting GLP-1 receptors, proven to support significant weight loss (15%+ in clinical trials) and metabolic improvement. Research protocols often use a 2.4mg subcutaneous weekly dose. Long-term studies show additional cardiometabolic and renal benefits.
    References: Top academic journals, FDA approval records.
  • Metabolic – MOTS-c:
    A mitochondrial peptide that improves glucose utilization, insulin sensitivity, and exercise endurance. Used in metabolic and aging research, MOTS-c is being explored for performance enhancement and resistance to metabolic stress.
    References: NIH, Frontiers in Physiology.
  • Nootropic – Semax:
    Semax is unique for cognitive resilience and neuroprotection; often delivered intranasally in studies. Research demonstrates enhancement in focus, memory, and stress adaptation.
    References: PubMed, Cognitive Vitality.

Peptide News

  • NAD+ (Category 1 FDA Bulks List): This peptide is essential for cellular energy and DNA repair. Recent FDA approval for compounding in research settings has expanded studies on mitochondrial health and aging.
    Latest clinical activity in metabolic disorder trials.
  • GHK-Cu (Copper Peptide): Recognized for its skin-regenerating and wound-healing properties, GHK-Cu is now accessible in certain compounding settings. Investigations show enhanced collagen synthesis and anti-inflammatory benefits.
    Recent FDA and cosmeceutical regulatory updates.
  • Changing FDA Landscape: Peptides like BPC-157 and TB-500 have been restricted from compounding in 2025, while research focus pivots to newer proteins approved under stricter safety and efficacy regulations.
    FDA bulks list updates: Regulatory news portal.

User Research Success

  • MOTS-c and Endurance: In a landmark study, MOTS-c administration led to increased athletic performance and lean muscle gain in challenging metabolic conditions. These findings are shifting protocols in exercise science and recovery research.
    References: NIH, Nature.

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